Currently data in deps.edn aliases or at the command line is read with edn/read[-string]. It would be useful to use the data_readers.clj[c] that are available on the classpath so tagged literal data can be used as well.
Main issue here is that the classpath is being computed based on what's read so this is probably not feasible. Subsequent changes have made deps.edn reading tolerant of unknown tagged data so it can be retrieved and used from the basis (rather than failing). Not planning to making any other changes here for now so closing.